Physicochemical properties, bond strength, and antibiofilm activity of a powder-gel bioceramic endodontic sealer
Year: 2025
Type: article
Abstract: Physicochemical properties, bond strength, and antibiofilm activity of a powder-gel bioceramic endodontic sealer, Sealer Plus BC (SPBC, MK Life, Porto Alegre, RS, Brazil), were evaluated in comparison with Bio-C Sealer (BCS, Angelus, Londrina, PR, Brazil), a reference bioceramic sealer, and AH Plus Jet (AHP, Dentsply DeTrey, Konstanz, Germany), a standard resin-based sealer. The setting time, pH, solubility, flow, and radiopacity were evaluated in accordance with ISO 6876:2012 standards. Bond strength was measured using the Push-Out test. Antibiofilm activity against Enterococcus faecalis alone or in combination with Candida albicans was assessed using a modified direct contact test with the eluate of fresh sealer (25 mg/mL) and after 24 hours of material setting. The data were analyzed using ANOVA and Tukey statistical tests (α = 0.05). SPBC exhibited higher Setting Time values compared to BCS and lower values compared to AHP (p < 0.05). BCS and SPBC had higher solubility values than 3% (p<0.05). BCS demonstrated flow values higher than those of SPBC and AHP (p<0.05). SPBC showed lower radiopacity (p<0.05) and higher bond strength (p<0.05) than BCS and AHP. SPBC and BCS exhibited alkaline pH throughout all evaluated periods. They demonstrated antimicrobial activity against Enterococcus faecalis and/or Candida albicans in the eluate of fresh sealer and 24 hours after setting (p < 0.05). In conclusion, SPBC powder-gel sealer, as a filling material, meets most ISO 6876 standards for physicochemical properties, demonstrates bond strength to dentin, and exhibits antimicrobial activity against both dual and single-specimen biofilms. However, it has a solubility greater than 3%.
Source: Brazilian Dental Journal
Institution: Universidade Estadual Paulista (Unesp)
Language: English
Subfield: Oral Surgery
Field: Dentistry
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $104
Awards: Evaluation of the root canal treatment procedures, physicochemical and biological properties of tricalcium silicate-based materials, G2855660360, Synthesis of new reparative biomaterial, evaluation of calcium silicate materials and analysis of the effect of the application of bioglass in the treatment of dentin and in the coating of Gutta percha in the interaction with bioceramic root canal sealers, G3754493184, G6073776786, G6525044959, G7529964825, G8715112064
OpenAlex ID: W4416865277