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Supplementary Figure S13 from ATOR-4066, a Bispecific Antibody Targeting CD40 and CEACAM5, Induces Strong Myeloid and T Cell–Dependent Tumor Immunity and Synergizes with PD-1 Blockade

Year: 2025

Type: supplementary-materials

Abstract: Supplementary Figure S13. Flow cytometry analysis of tumor, lymph node and spleen from mice day 11 post MC38-CEA inoculation, following two treatments, day 6 and day10, of vehicle, 100ug CD40 mab or 167ug ATOR-4066. MFI of CD86 and PDL1 in macrophages, monocytes and dendritic cells in tumor

DOI: 10.1158/2326-6066.30761381

Authors: Hampus Andersson, Ida Uddbäck, Tova Hermodsson, Mona Celander, Amulya Krishna Shetty, Lill Ljung, Anneli Nilsson, Anette Sundstedt, Laura von Schantz, Laura A. Varas, Mattias Levin, Anna Säll, Dietmar Weilguny, Kim Jansson, Sara Fritzell, Karin Hägerbrand, Malin Lindstedt, Peter Ellmark

Language: English

Topic: Cancer Immunotherapy and Biomarkers

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4416901428

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