Considerations and perspectives on phage therapy from the transatlantic taskforce on antimicrobial resistance
Year: 2025
Type: review
Abstract: Amid rising antimicrobial resistance and limited antibiotic innovation, bacteriophages are gaining attention as potential therapeutics across human health, animal, and food sectors. Despite historical use, their clinical application in humans remains constrained by scientific, industrial, and regulatory challenges. To address these issues, the Transatlantic Task Force on Antimicrobial Resistance (TATFAR) convened sessions with experts from member parties. This perspective synthesizes insights from the TATFAR group, highlighting regulatory differences, research gaps, and opportunities for international collaborations to advance bacteriophage therapy.
Source: Nature Communications
Authors: Kyung Moon, Carmen Coxon, Christine Årdal, Radu Botgros, Sarah Djebara, Laura Durno, Cara R. Fiore, Jean-Baptiste Perrin, Dennis M. Dixon, Marco Cavaleri
Institutions: National Institutes of Health, National Institute of Allergy and Infectious Diseases, Norwegian Institute of Public Health, European Medicines Agency, Queen Astrid Military Hospital, Health Canada, Center for Biologics Evaluation and Research, United States Food and Drug Administration, European Commission
Language: English
Subfield: Virology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $6,990
OpenAlex ID: W4416986932