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An Outbreak of Respiratory Infection due to Respiratory Syncytial Virus Subgroup B in Ankara, Turkey

Year: 2004

Type: article

Abstract: During the outbreak, from 16 January 2002 to 3 March 2002, nasopharyngeal secretions obtained from 35 pediatric patients under 2 years of age and suffering from acute respiratory disease were tested by VIDAS respiratory syncytial virus (RSV) assay (an automated enzyme-linked fluorescent immunoassay) and reverse transcription- polymerase chain reaction (RT-PCR). RSV antigen was detected in 16 specimens by VIDAS RSV assay, and 15 of these were confirmed by the RT-PCR. A total of 18 samples were found to be positive by RT-PCR. RSV subgroup B was identified by further restriction fragment length polymorphism analysis using AvaII and BglII endonucleases in 17 of 18 (94%) RT-PCR positive samples. These findings indicated that RSV subgroup B was highly dominant during an outbreak of RSV infection among children in Ankara. To our knowledge, this is the first outbreak due to dominant RSV subgroup B documented in Turkey.

Source: Japanese Journal of Infectious Diseases

DOI: 10.7883/yoken.jjid.2004.178

Authors: Cakır Guney, Ayhan Kubar, Mehmet Yapar, A. Bulent Besirbellioglu, Levent Doganci

Institutions: Gülhane Askerî Tıp Akademisi, Turkish Armed Forces

Language: English

Topic: Respiratory viral infections research

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W51223378

FWCI: 0.666

Cites: 9

Cited by: 8

Related to: 10