Year: 1972
Type: article
Study design: Observational Study
Abstract: A B S T R A C T 50 Caucasian children with acute lymphocytic leukemia (ALL) and 219 members of their families have been genotyped for 15 antigens of the HL-A system.The antigen and gene frequencies for HL-A2 were significantly higher in the patient population than in a 200 member normal Caucasian panel.No other antigen frequencies were significantly elevated.All antigens typed for were found in the patients.No antigen gain or loss was detected in the leukemic cells.* The paternal chromosome's haplotype is listed first in the patient and the normal siblings.The normal sibling (italicized) is the closest in age to the patient.§ X is an unknown antigen.Parentheses indicate a deduced genotype in a parent who was not typed.¶ Identical twin with the patient.
DOI: 10.1172/jci107055
Authors: G. Nicholas Rogentine, R. A. Yankee, J. J. Gart, J. Nam, R. J. Trapani
Institutions: National Institutes of Health, National Cancer Institute
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W52984346