Traditional Phytomedicine and Enzymatic Modulation in Neurodegenerative Disorder Prevention
Year: 2025
Type: book-chapter
Abstract: Recent pharmacological strategies have begun to explore the role of enzymatic pathways in slowing or reversing disease progression. Alongside modern drug development, traditional phytomedicine offers a largely untapped reservoir of bioactive compounds that may influence key enzymes implicated in neurodegeneration. This chapter presents an ethnobotanical study conducted in Talassemtane National Park (Northern Morocco), documenting medicinal plants traditionally used for the treatment of nervous system disorders. Through a pharmacological review of selected species, we highlight their potential to modulate enzymatic and oxidative pathways particularly through antioxidant, anti-inflammatory, and neuroprotective mechanisms. In addition, they are capable of interacting with targets such as acetylcholinesterase and neuroinflammatory mediators. By integrating traditional knowledge with pharmacological and biochemical analysis, we propose that phytomedicines from Mediterranean biodiversity can contribute to enzyme-based therapeutic strategies in neurodegeneration.
Source: IGI Global eBooks
Authors: Mariam Rhattas, Rajaa Kaddar, Karima Rhattas, Yassine Mouniane, Brahim El Ouardi, Imane Aitouhanni, Ouafae El Yahyaoui, Sanae Masmoudi, Mohamed Belomaria, Mohamed El Bakkali
Language: Ndonga
Subfield: Complementary and alternative medicine
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W7108329579