Spontaneous pathological splenic rupture as a first manifestation of mantle cell lymphoma – a case report and literature review
Year: 2025
Type: article
Study design: Case Report
Abstract: Splenic rupture is a critical surgical condition that poses an immediate threat to the patient's life. In most cases, mechanical trauma to the organ results in the rupture of the capsule, leading to hemorrhage into the peritoneal cavity. Spontaneous (pathological) spleen rupture (SPSR) is considered when the etiology of the rupture is non-traumatic. Spontaneous (pathological) spleen rupture is most commonly associated with hematological malignancies, though it remains a rare condition. Only 8 cases have been caused by mantle cell lymphoma (MCL). This review presents the case of a 59-year-old male patient who was treated with emergency splenectomy due to SPSR. Histopathological examination revealed MCL.
Source: Polish Journal of Pathology
Authors: Antoni Knera, Wojciech Ciesielski, Adam Placek, Piotr Kruszyński, Marcin Braun, Julia Sołek, Janusz Strzelczyk, Adam Durczyński, Tomasz Klimczak, Piotr Hogendorf
Institution: Medical University of Lodz
Language: English
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $218
OpenAlex ID: W7115190876
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