Exploring the Therapeutic Potential of Tamarix aphylla Extract: Antioxidant Properties, Antiproliferative Effects, and Cytotoxicity Assessment
Year: 2025
Type: article
Abstract: Background: The use of plants for cancer prevention and therapy has attracted more interest recently due to the large diversity of phytochemical components found in plants and their decreased adverse effects. This study evaluated the cytotoxic capacity of a single medicinal plant species Tamarix aphylla from Al-Hilla, Babylon Governorate, Iraq, against two cell lines: one normal cell line and one cancerous cell line. It also evaluated the antioxidant activity of the plant species. Methods: The MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-dipenyltetrazolium bromide] assay was used to measure the antioxidant activity of the extracts utilizing various assays, including DPPH radical scavenging activity and reductive ability. Results: When applied at the same concentrations, the Tamarix aphylla extract significantly affected the cancer cell line (MCF-7) more than the normal cell line (REF52). The extract's impact on the two lines varied noticeably from one another. Tamarind plants have demonstrated a significant level of antioxidant efficacy. Conclusions: This study concluded that alcoholic extract of Tamarix aphylla has a strong anti-free radical effect. In addition inhibits the growth of MCF-7 breast cancer.
Authors: Mohammed S. Algoraby, Khalid H. Alobaidi
Institution: Nahrain University
Language: English
Topic: Medicinal Plant Research
Subfield: Plant Science
Domain: Life Sciences
Open Access status: diamond
Funder: Al-Nahrain University
OpenAlex ID: W7117487396