In-Hospital Outcomes of Neonates with Perinatal Asphyxia at a Tertiary Care Center in North India
Year: 2026
Type: article
Study design: Observational Study
Abstract: Background: Perinatal asphyxia remains a major contributor to neonatal morbidity and mortality in low- and middle-income countries. This study evaluates the clinical profile and immediate in-hospital outcomes of neonates with perinatal asphyxia at a tertiary care hospital in North India. Methods: A prospective observational study was conducted over 18 months at G.B. Pant Hospital, Srinagar. Term neonates admitted within 24 hours of birth with APGAR score <6 at 5 minutes and features of hypoxic-ischemic encephalopathy (HIE) were included. Data on socio-demographic factors, delivery details, interventions, and outcomes were analyzed. Results: Of 217 neonates, 54.8% were male. HIE was present in 78.8% (Grade II: 55%, Grade I: 29.2%, Grade III: 15.8%). Mortality occurred in 14.3%, with 92.6% mortality in HIE Grade III. Prolonged labour (33.6%) and meconium-stained liquor (22.5%) were the most frequent antenatal complications. Oxygen therapy was the commonest intervention (76–87% in HIE I–No HIE). Conclusion: Perinatal asphyxia continues to result in significant mortality, particularly in severe HIE. Early referral and improved intrapartum care may improve survival.
Authors: Mohd Suhail Jogi, Samiya Khan, Danish Rafiq
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W7121505145