Year: 2026
Type: article
Abstract: Rapid advances in oncology have led to unprecedented pharmacological and technological complexity, yet these developments have not always translated into meaningful benefits for patients. Inspired by the Common Sense Oncology movement, this article reflects on the need to recalibrate cancer care beyond biologistic and industry-driven models. We argue for a broader, patient-centred vision of oncology that integrates social determinants of health, prevention, supportive and palliative care, shared decision-making and independent research alongside pharmacological innovation. Drawing on evidence from health economics, clinical research trends and public health, we highlight the paradox between rising oncology expenditures and limited gains in overall survival, quality of life and equity. We also discuss the growing influence of industry-sponsored research, the increasing reliance on surrogate endpoints, and the underfunding of non-pharmacological and psychosocial interventions. Finally, we propose concrete priorities for policymakers, clinicians and research institutions to ensure that oncology progress remains aligned with outcomes that truly matter to patients.
Source: ecancermedicalscience
Authors: Rodrigo Lastra, Patricia Iranzo, Javier-David Benítez-Fuentes, Ana Callejo, Mara Cruellas, Jacobo Gómez Ulla, Isabel Pimentel, José Luis Pérez-Gracia, Marta Ramos, Francisco Gil Moncayo, María Álvarez Alejandro, Marta Gascón, Sergio Martínez Recio, Pilar Rivero, Jorge Bartolomé, Antonio David Lázaro Sánchez, David Fernández Garay, Alicia de Luna Aguilar, Isabel Lorenzo Lorenzo, Joan Brunet, Noemi Reguart, Dario Trapani
Institutions: Hospital Clínico Universitario Lozano Blesa, Vall d'Hebron Hospital Universitari, Vall d'Hebron Institute of Oncology, Hospital General Universitario de Elche, Hospital Universitario de Burgos, Clinica Universidad de Navarra, Universidad de Navarra, Institut Català d'Oncologia, Hospital Universitario Miguel Servet, Hospital de Sant Pau, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Santa Lucía University General Hospital, Hospital Regional Universitario de Málaga, University Hospital Complex Of Vigo, Consorci Institut D'Investigacions Biomediques August Pi I Sunyer, University of Milan, European Institute of Oncology
Language: English
Subfield: Economics and Econometrics
Domain: Social Sciences
Open Access status: gold
Estimated APC paid: $1,226
OpenAlex ID: W7124461024