Year: 2026
Type: review
Abstract: Atopic dermatitis (AD) is a chronic, non-infectious disease that most often begins in childhood.It is characterized by itchy erythematous lesions located mainly on the flexural surfaces, as well as dry skin and lichenification.The pathogenesis of atopic dermatitis consists of immunological, genetic, and environmental aspects that start the dysfunction of the epidermal barrier and promote dysregulation of the immune response.This entire process leads to chronic inflammation, and it is related to oxidative stress.Studies confirm that bioactive compounds, plant extracts, and hydrogels have important antioxidant and anti-inflammatory properties.Moreover, they are able to control reactive oxygen species (ROS) production due to antioxidant therapies, which may become a promising strategy for treating AD.The introduction of such therapeutic strategies could help improve the quality of life for patients with atopic dermatitis and reduce the symptoms associated with this chronic skin disease.This piece aims to explore the aspect of oxidative stress in the pathogenesis of atopic dermatitis and to evaluate the efficacy of various antioxidant therapies with a focus on their therapeutic potential.
Source: Medical Science
Language: English
Subfield: Dermatology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W7127044117