Cycloalkylation reactions ofortho-chlorophenol with 1(3)-methylcyclohexenes in the presenceof KU-23 catalyst
Year: 2026
Type: article
Abstract: The article presents the results of studies of the cycloalkylation reactions of ortho-chlorophenol with 1-methylcyclohexene and 3-methylcyclohexene using the KU-23 catalyst.The cycloalkylation reaction of ortho-chlorophenol with 1(3)-methylcycloalkenes was carried out in a batch reactor under laboratory conditions.After the reaction, the alkylate is separated from the catalyst and rectified.During the rectification, first, at atmospheric pressure (up to 200 °C), unreacted cycloalkenes and ortho-chlorophenol are removed, and then the desired reaction product is removed under vacuum (10 mm Hg).Tod etermine the optimal conditions ensuring the maximum yield of 4-methylcycloalkyl-2chlorophenols, the effect of temperature, reaction time, molar ratio of orthochlorophenol to 1(3)-methylcycloalkenes, and the amont of catalyst on product yield and selectivity was studied.The reaction temperature was in the range of 70 -130 °C, the duration of the experiments was 2 -6 h, the molar ratio of ortho-chlorophenol to 1(3)-methylcyclohexene was in the range of 2:1; 1:1; 1:2 and the amount of catalyst relative to ortho-chlorophenol was in the range of 5 -15%.As a result of the study of the cycloalkylation reactions of orthochlorophenol with 1-methylcyclohexene and 3-methylcyclohexene using the KU-23 catalyst, optimal conditions were found: the reaction temperature was 110-115 °C, the duration of the experiment was 4-5 h, the molar ratio of orthochlorophenol to cyclohexane was 1:1 and the amount of catalyst was 10% based on the ortho-chlorophenol taken.Under these conditions, the yield of 4[1(3)methylcyclohexyl]-2-chlorophenols are 74.3 -77.2% based on the orthochlorophenol used, and the selectivity to the target product is 92.5-94.3%.After the target products were separated from the alkylate, their physicochemical properties, elemental composition, and molecular mass were determined, and their chemical structures were confirmed using IR and 1 H NMR spectroscopy
Source: PPOR
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: bronze
OpenAlex ID: W7127046700