Work

Gut check: antimicrobial stewardship opportunities in intra-abdominal infections

Year: 2026

Type: article

Abstract: Intra-abdominal infections (IAIs) are common in both the inpatient and outpatient setting but are not often a target for antimicrobial stewardship programs (ASP). However, IAIs provide ASPs an opportunity to translate evidence into practice while also addressing empiric broad-spectrum antibiotic use and establishing relationships with surgical stakeholders. In this review, we analyze five areas of emerging evidence within this heterogeneous field that merit close attention from ASPs, including spontaneous bacterial peritonitis prophylaxis, antibiotic management of appendicitis and biliary tract infections, and optimal amoxicillin-clavulanate and metronidazole dosing.

Source: Antimicrobial Stewardship & Healthcare Epidemiology

DOI: 10.1017/ash.2025.10169

Authors: Ritika Prasad, Radhika Arya, Natalie Medvedeva, David Ha, Marisa Holubar

Institutions: Stanford Health Care, Stanford Medicine, Stanford University

Language: English

Topic: Antibiotic Use and Resistance

Subfield: Applied Microbiology and Biotechnology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,719