Clinico-Demographic Trends in Inherited Bleeding Disorders: Insights from Dhaka Medical College
Year: 2026
Type: article
Study design: Observational Study
Abstract: Background: The blood coagulation system is very delicately balanced; is maintained in a fluid state in the vasculature and rapidly clots to seal an injury. This study aims to determine the demographic and clinical pattern of bleeding disorders. Materials and Methods: This prospective type of cross-sectional study comprised 112 patients with bleeding or a history of bleeding in the Department of Haematology and Bone Marrow Transplantation Unit, Dhaka Medical College Hospital, Dhaka, from January to December 2016. Patients were examined for clinical presentation and underwent haematological investigations to arrive at a diagnosis. The data was obtained, tabulated and analysed by using SPSS 22. Results: In this study, 81.2% of patients suffered from congenital coagulation factors deficiency, and haemophilia was found to be the most common congenital haemostatic defect (61.6%). Bleeding disorder was found predominantly among males in 86.6% compared to females (13.4%). 1st-degree consanguinity was mainly observed in Glanzmann thrombasthenia and Von Willebrand Disease. History of prolonged bleeding was statistically associated with clinical diagnosis of the patient (p<0.01). Conclusions: Haemophilia A and B were found as the leading causes of bleeding disorder. Von Willebrand Disease (VWD) also played a role and Glanzmann thrombasthenia was the most common one that had been identified among other disorders.
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7127054388