Work

Integrated single-cell analyses of affinity-tested B cells enable the identification of a gene signature to predict antibody affinity

Year: 2026

Type: article

Source: Cell Systems

DOI: 10.1016/j.cels.2025.101483

Authors: Michele Chirichella, Matthew Ratcliff, Shuang Gu, Ricardo J. Miragaia, Massimo Sammito, Valentina Cutano, Suzanne Cohen, Davide Angeletti, Xavier Romero-Ros, Darren J. Schofield

Institutions: AstraZeneca (United Kingdom), University of Gothenburg

Language: English

Topic: Monoclonal and Polyclonal Antibodies Research

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: AstraZeneca, Knut och Alice Wallenbergs Stiftelse, Vetenskapsrådet, European Research Council

Awards: G2047280965, Influenza-specific memory B cells in the mucosa - differentiation, specificity and protective role, G3820265075, G7724392301

OpenAlex ID: W7127563294

FWCI: 6.4

Cites: 88

Cited by: 3

Related to: 10