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Rare Case of Pilomatricoma of the Leg in a Young Patient: A Case Report

Year: 2026

Type: article

Abstract: Pilomatricoma, a benign neoplasm originating from the hair follicle, typically occurs in the head and neck region. However, its occurrence in the leg is rare. We present a case of a young patient with a palpable mass on the leg. Physical examination revealed a 2 cm firm, non-tender subcutaneous nodule. Imaging studies (ultrasound and MRI) confirmed the diagnosis of pilomatricoma. The patient underwent successful surgical excision under general anesthesia, achieving clear margins. Histopathological examination demonstrated characteristic features, including basaloid cells, ghost cells, and calcifications, with no evidence of malignancy. Regular follow-up visits showed no recurrence several months postoperatively. Pilomatricoma is typically found in the head and neck region, making its occurrence in the leg extremely rare. Differential diagnosis includes lipomas, dermoid cysts, and neurofibromas. Radiological imaging, particularly ultrasound, aids in preoperative diagnosis by demonstrating characteristic features. Surgical excision with clear margins is the mainstay of treatment, ensuring complete removal and reducing the risk of recurrence. We report a rare case of pilomatricoma of the leg, highlighting the importance of considering this diagnosis even in uncommon anatomical locations. Surgical excision with clear margins resulted in successful management without recurrence. Awareness of atypical presentations of pilomatricoma is crucial for accurate diagnosis and appropriate management in clinical practice.

Source: World Journal of Advanced Research and Reviews

DOI: 10.30574/wjarr.2026.29.2.0205