Work

Development of bioactive SF/HAp/ZnO scaffolds incorporating succinic acid with potential bone regeneration capabilities

Year: 2026

Type: article

Abstract: biocompatibility studies using calcein, DAPI, and PI staining (live/dead assay) confirmed that the SA-functionalized scaffold was non-toxic and supported high viability of MC3T3-E1 pre-osteoblasts after 48 hours. The findings indicated that the use of succinic acid delayed the degradation time. This multifunctional composite scaffold showed great potential for use in bone tissue engineering.

Source: RSC Advances

DOI: 10.1039/d5ra04926a

Authors: Sadia Habib, Aysha Arshad, Hafsah Akhtar, Fahad Hussain Alhamoudi, Gülderen Karakuş, Gültekin Gökce, Aqif Anwar Chaudhry, Hamad Khalid, Ather Farooq Khan

Institutions: COMSATS University Islamabad, COMSATS University Islamabad, Lahore Campus, King Khalid University, Sivas Cumhuriyet Üniversitesi

Language: English

Topic: Bone Tissue Engineering Materials

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,042

Funders: Deanship of Scientific Research, King Khalid University, Ministry of Science and Technology, Pakistan, King Khalid University

Award: G5923898939

OpenAlex ID: W7129434231

FWCI: 1.495

Cites: 62

Cited by: 1

Related to: 10