Work

Cost‐Effectiveness of Automated Insulin Delivery Systems in Paediatrics, T1D and T2D Adults Across Four Nordic Countries

Year: 2026

Type: article

Abstract: ABSTRACT Aims This study evaluated long‐term cost‐effectiveness of automated insulin delivery (AID) systems versus multiple daily injections (MDI) + CGM in children with type 1 diabetes (T1D), adults with T1D and insulin‐treated individuals with type 2 diabetes (T2D) across Denmark, Finland, Norway and Sweden. Materials and Methods Clinical outcomes and economic footprints were analysed for horizons up to 50 years from a healthcare system perspective using the IQVIA Core Diabetes Model. Five patient profiles were modelled: T1D paediatrics (T1D‐Paed), T1D adults with high baseline HbA1c (T1D‐Adult), real‐world evidence in T1D adults with lower baseline HbA1c (T1D‐Adult RWE ), T2D adults (T2D‐Adult) and older T2D adults (T2D‐Elder). Costs were inflated to July 2024, with 3% annual discounting. Sensitivity analyses explored scenarios varying time horizons and HbA1c effect sizes and inclusion of hypoglycaemia rates. Results AID systems were estimated to lead to a reduction in diabetes‐related complications in all groups, most notably in the T1D‐Adult group (318 vs. 542 complications per 100 individuals). Improvements translated into lifetime cost savings (€1435 to €26 259), increased life expectancy (LE) and more quality‐adjusted life years (QALYs). Incremental cost‐effectiveness ratios (ICERs) remained below willingness‐to‐pay thresholds in all countries (from €14 695/QALY for T1D‐Adult in Finland to €56 711/QALY for T1D‐Adult RWE in Denmark), confirming AID is cost‐effective across all groups in the Nordic region. Conclusions AID therapy consistently projected reduced diabetes‐related complications while remaining cost‐effective across a broad spectrum of diabetes patient profiles in the Nordic region. These findings strengthen the case towards widespread integration of AID technology into national diabetes care frameworks.

Source: Diabetes Obesity and Metabolism

DOI: 10.1111/dom.70658

Authors: Johan Jendle, Kirsten Nørgaard, Elina Pimiä, Heiko Bratke, Aesha Khan Mirón, Maria‐Eleni Syleouni