Cerebrovascular dysfunction as a link between stroke and Alzheimer’s disease
Year: 2026
Type: dissertation
Abstract: This dissertation aims to address how ischemic injury induces cerebrovascular dysfunction and triggers a pathological cycle to accelerate the onset and progression of Alzheimer's disease pathology and cognitive decline. I investigated connections between the cognitive, vascular, and histopathological changes that occur after stroke and how they relate to AD.
Source: OHSU Digital Commons
DOI: 10.6083/bpxhc44959
Author: Woodruff, Simone
Institution: Oregon Health & Science University
Language: English
Subfield: Neurology
Field: Neuroscience
Domain: Life Sciences
Open Access status: green
Awards: Glial regulation of neurovascular coupling in CNS disorders, Astrocyte regulation of cerebral blood flow at the intersection of ischemia and Alzheimer's disease, Neuroscience of Aging, Neurodegeneration and Alzheimer's Disease, Medical Scientist Training Program of Oregon Health & Science University, Contribution of endothelin 1 mediated ischemic vascular dysfunction to Alzheimer's disease
OpenAlex ID: W7138998793