Diagnostic Accuracy of Ultrasound for Acute Appendicitis Compared with Histopathological Findings
Year: 2025
Type: article
Study design: Observational Study
Abstract: Background: Acute appendicitis is one of the most common surgical emergencies worldwide. Ultrasound is widely used as a first-line imaging modality; however, histopathological examination remains the gold standard for confirming the diagnosis. Objective: To evaluate the diagnostic accuracy of ultrasound compared with histopathological findings in patients with suspected acute appendicitis. Methods: A diagnostic accuracy study was conducted on 125 patients with suspected acute appendicitis at Tobruk Medical Centre between January and December 2021. All patients underwent preoperative ultrasound examination followed by appendectomy and postoperative histopathological evaluation. Data were analysed using the Chi-square test, and a p-value <0.05 was considered statistically significant. Results: Among the 125 patients, histopathological examination confirmed acute appendicitis in 106 cases (84.8%). Ultrasound demonstrated a sensitivity of 95.1%, specificity of 66.7%, positive predictive value of 90.4%, and negative predictive value of 80.3%, with an overall diagnostic accuracy of 89.6%. Conclusion: Ultrasound is a highly sensitive and useful first-line imaging modality for the diagnosis of acute appendicitis; however, its moderate specificity limits its ability to definitively confirm the diagnosis. Ultrasound should therefore be interpreted alongside clinical assessment and other diagnostic findings.
DOI: 10.64516/bzvhd360
Authors: Faraj A. Aljali, Fathi A. Abdalla Asnini
Institution: Tobruk University
Language: English
Subfield: Emergency Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7140119087