Work

Mucormycosis in patients with diabetes mellitus in Russia: registry data analysis

Year: 2026

Type: article

Abstract: We observed 100 patients with mucormycosis from 2002 to 2024. We used the EORTC/MSGERC 2019, 2020 criteria for diagnosing mucormycosis. Mucormycosis developed against the background of type 2 diabetes mellitus in 10% of patients, type 1 in 7%, in 83% – after coronavirus infection COVID-19 and glucocorticosteroid therapy. The average glycemia level on the day of diagnosis of mucormycosis was 17 mmol / l. Other risk factors were ketoacidosis – 48%, use of glucocorticosteroids – 85%, lymphocytopenia 44%. The main clinical variant was rhinoorbitocerebral mucormycosis – 93%. Less frequently were mucormycosis of brain (37%), skin (25%), lungs (8%), kidneys (1%). Antifungal therapy was used in 96% of patients: рosaconazole (69%), amphotericin B deoxycholate (59%), lipid forms of amphotericin B (25%), isavuconazole (17%). Surgical treatment used 97%. 12 weeks overall survival was 80%.

Source: Journal Infectology

DOI: 10.22625/2072-6732-2026-18-1-5-17

Authors: S. N. Khostelidi, S. A. Vartanyan, A. O. Charushin, A. V. Vagin, O. P. Kozlova, T. S. Bogomolova, S. M. Ignatyeva, Yu. L. Avdeenko, Yu. V. Borzova, N. V. Vasilyeva

Institutions: North-Western State Medical University named after I.I. Mechnikov, Perm State Medical Academy

Language: English

Topic: Antifungal resistance and susceptibility

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7142289413

FWCI:

Cites: 44

Cited by:

Related to: 10