Comparative Evaluation of Efficacy of Topical Lidocaine Spray, Tetrafluoroethane Spray and Orachill Before Intraoral Local Anesthesia – A Double Blind Randomized Clinical Trial
Year: 2026
Type: article
Study designs: Randomized Controlled Trial, Clinical Trial
Abstract: Topical and local anesthesia is the cornerstone of the treatment in this modern-day dentistry. Background: Local anesthetics, one of the most used drugs to avert and manage pain, are associated with pain resulting from the situation's irony. Efforts are made to reduce this pain perception of injection. Along with lidocaine as topical anesthesia, cryoanesthesia has also reduced injection pain. Aim: To evaluate the efficacy of lidocaine spray, tetrafluoroethane spray, and orachill mouthpiece concerning discomfort during needle insertion in pediatric patients for various dental procedures measured by Sound, Eye & Motor scale (SEM) (objective method), Visual Analog Scale (VAS) (subjective method), Wong-Baker Faces Pain Rating scale (WBFPRS) (subjective method) pain scales. Study Design: In this double-blind, randomized clinical trial, 90 patients between the age group of 5 and 12 years were selected and randomly divided into three equal groups with 30 patients in each group. The three groups into which the study sample was divided were; Group 1 was lidocaine spray, Group 2 was tetrafluoroethane spray, and Group 3 was the orachill group. Results: The mean of SEM for the sound score was 1.23+0.89; 0.93+0.64; 0.90+0.71 for lidocaine spray, tetrafluoroethane spray, and orachill group, respectively. The mean score for the eye was 1.23+ 1; 0.87+0.68; 0.73 +0.69 lidocaine spray, tetrafluoroethane spray, and orachill group, respectively. The mean score for the motor score was 1.20+0.76; 0.73+0.64; 0.97+0.67 for lidocaine spray, tetrafluoroethane spray, and orachill group, respectively. The mean WBFPS scores were found to be highest in Group 1 (3.80+ 1.42), followed by Group 2 (3.47 + 1.57), and the scores were lowest in Group 3 (2.53 + 1.66). The mean VAS scores were found to be highest in Group 1 (3.87+ 1.78), followed by Group 2 (3.23 + 1.22), and the scores were lowest in Group 3 (2.20+ 1.49). Conclusion: The efficacy of the Orachill mouthpiece proved to be superior in comparison to lidocaine spray as a topical anesthetic agent. Orachill mouthpiece was comparable in efficacy to Tetrafluoroethane as a topical anesthetic agent.
Institutions: Government Medical College, Santosh University
Language: English
Subfield: Oral Surgery
Field: Dentistry
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W7148628600