Characterization and Biological Screening of Bioactive Compounds from Trachyspermum ammi
Year: 2026
Type: article
Abstract: Antimicrobial Resistance of fungal infections to drugs presently used are major problem for curing those infections. The aim of this study is to analyze the potential of Trachyspermum ammi seed extract against fungal pathogens. The chemical composition of ethyl acetate extract of Trachyspermum ammi seeds sample was assessed using gas chromatography-mass spectrometry (GC-MS). Evaluation of antifungal activity of the extract was analyzed by agar well diffusion method against fungal pathogens Aspergillus fumigatus, Mucor racemosus, Penicillium chrysogenum and Candida albicans with various concentrations of extracts such as 25μg/ml, 50μg/ml, and 100μg/ml. Zone of inhibition was measured and calculated. Thirteen monoterpene hydrocarbons (57.6%) and oxygenated monoterpenes (42.4%) compounds were identified in the ethyl acetate extract of T. ammi. T. ammi extract was capable of inhibiting the growth of fungal pathogens when compared with positive control Amphotericin-B. This antifungal action was due to the secondary metabolites which are present in the extract.
Institution: Vels University
Language: English
Subfield: Food Science
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W7153003263