Year: 2026
Type: article
Study design: Observational Study
Abstract: Objective: This study aimed to examine whether benign joint hypermobility syndrome (BJHS) affects bone mineral density (BMD). Materials and Methods:A cross-sectional controlled design was used.Seventy-two participants were enrolled: 36 patients diagnosed with BJHS (group 1) and 36 healthy individuals (group 2).Participants aged ≥18 years were included.BJHS was diagnosed according to Beighton criteria with a score ≥4.Individuals with secondary osteoporosis, inflammatory rheumatic disease, systemic illness, pregnancy, liver or kidney failure, spinal or hip fractures, metal implants, or the use of medications affecting bone metabolism were excluded.BMD of the lumbar spine and femur was measured by dual-energy X-ray absorptiometry and reported as absolute values and T and Z-scores.Results: Group 1 and group 2 had mean ages of 29.74±7.97and 32.02±7.73years, and mean body mass index (BMI) values of 23.51±2.84and 24.76±3.17,respectively.No significant differences were found between groups regarding age, sex, BMI, or biochemical parameters.All T and Z-scores were significantly lower in BJHS patients compared with healthy controls (p<0.05).Conclusion: Patients with BJHS demonstrated reduced BMD, suggesting that hypermobility may negatively affect bone structure.Individuals with BJHS should be assessed for osteopenia or osteoporosis as part of routine evaluation.
Source: Turkish Journal of Osteoporosis
Authors: Bilal Uysal, Nilay Şahin
Institution: Balıkesir University
Language: Turkish
Subfield: Genetics
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W7153123728
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