Year: 2026
Type: article
Study design: Observational Study
Abstract: Aim. To compare diagnostic value of various indicators of peripheral artery atherosclerosis in relation to the of stenotic coronary atherosclerosis. Material and methods . The study included 120 patients aged 40‑64 years. All patients underwent duplex ultrasound of the carotid arteries and lower extremity arteries. Coronary atherosclerosis was assessed using invasive coronary angiography and/or multislice computed tomography with determination of the coronary calcium score. Results. Clinically significant coronary atherosclerosis was detected in 60 patients (50,0%), and severe lesion — in 25 (20,8%). The diagnostic efficiency of ultrasound indicators of lower extremity artery involvement and the burden of systemic atherosclerosis, assessed by the area under the receiver operating characteristic curve (ROC) and the Youden index for coronary atherosclerosis, was higher than that for carotid atherosclerosis indicators. However, when comparing the AUC for different indicators, no significant differences were revealed. A significant increase in AUC for the diagnostic model for clinically significant coronary atherosclerosis was observed when adding the maximum degree of stenosis of the lower extremity arteries, the plaque number in lower extremity arteries, and the ABS score to the standard risk assessment algorithm. A significant increase in the AUC for the diagnostic model for severe coronary atherosclerosis was observed when the maximum degree of carotid stenosis and the number of atherosclerotic plaques in the lower extremity arteries were added to the standard algorithm for assessing the coronary atherosclerosis risk. Conclusion . Among patients aged 40‑64 years, ultrasound indicators of peripheral artery atherosclerosis demonstrated moderate to high diagnostic value for coronary atherosclerosis. Adding the maximum degree of stenosis in the lower extremity arteries, the plaque number in the lower extremity arteries, and the ABS score to the standard algorithms for assessing cardiovascular risk significantly increased the diagnostic efficacy of the diagnostic model for clinically significant coronary atherosclerosis.
Source: Russian Journal of Cardiology
Institution: Chelyabinsk State Medical Academy
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7163516640