Resolution of oxidative stress on dandruff scalps with Ayurvedic anti-dandruff regime: a clinical study
Year: 2026
Type: article
Study design: Clinical Trial
Abstract: Background: This study is aimed to evaluate the efficacy and safety of ayurvedic anti-dandruff regime (Indulekha - Svetakutaja oil and dandruff treatment shampoo) in the management of dandruff in healthy, Indian participants suffering from dandruff. Methods: A total of 53 subjects with clinically diagnosed moderate dandruff were selected based on inclusion and exclusion criteria. Study was conducted in 3 phases, wash-off phase for 2 weeks, treatment phase for 4 weeks, followed by a regression phase of 2 weeks (during which ayurvedic anti-dandruff regime was withdrawn). Participants applied anti-dandruff regime on their scalp as per the instructions provided. Results: After 4 weeks of treatment, ayurvedic anti-dandruff regime demonstrated a significant reduction in dandruff flakes in 100% of participants, resolution of scalp itch in 100% participants with reduced levels of histamines (by 30%) and oxidative stress marker on scalp as measured by 13-hydroxyoctadecadienoic acid (HODE) by 50%. There were no reported side effects like oiliness/redness/irritation, during treatment and regression phase. Conclusions: Ayurvedic anti-dandruff regime is a safe and highly effective solution designed to combat dandruff and oxidative stress on scalp, while simultaneously improved overall health of the scalp and hair.
Institution: Unilever (India)
Language: English
Topic: Nail Diseases and Treatments
Subfield: Dermatology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7165580428