A Systematic Literature Review and Feasibility Assessment of an ITC for the Prevention of Pressure Injuries using Dressings in Moderate- to High-Risk Patients
Year: 2026
Type: preprint
Abstract: The purpose of this project is to conduct a systematic literature review (SLR) to evaluate the clinical evidence on foam wound dressings used for sacral pressure injury (PI) prevention in adults at moderate to high risk, and to assess feasibility for an indirect treatment comparison (ITC). We will determine how effectively these dressings prevent PIs compared with standard‑of‑care protocols with or without alternative dressings. Methods will follow the Centre for Reviews and Dissemination and Cochrane guidance and align with PRISMA standards. Searches will be executed in MEDLINE, Embase, and CENTRAL, supplemented by conference proceedings, trial registries, cross‑checking of recent SLRs, and LitMaps similarity searching. Dual independent screening and double‑extraction with verification will be performed, with discrepancies adjudicated by a third reviewer. Risk of bias will be appraised using Cochrane tools, with results summarized in an analysis‑ready Excel workbook and a PRISMA flow diagram.
Source: OSF Preprints (OSF Preprints)
Language: English
Subfield: Dermatology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7166258773