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The importance of assessing the constitutional type in children with chronic H. Pylori-associated gastroduodenitis to determine treatment and diagnostic tactics

Year: 2026
Type: article
Study design: Observational Study
Abstract: Aims. To study the features of the course of chronic H. pylori-associated gastroduodenitis in children of three types of constitution and to develop a management algorithm for each of them. Materials and methods. The analysis of the examination data of 250 patients with a diagnosis of Chronic gastroduodenitis aged 4 to 17 years, selected in the study group according to the inclusion and exclusion criteria, was carried out. The age and sex composition, features of the clinical course of the disease, infection with the bacterium H. pylori, data from laboratory and instrumental studies, and the effectiveness of eradication antihelicobacter therapy were evaluated. Based on the data obtained, a therapeutic and diagnostic algorithm for the management of asthenics, normosthenics and hypersthenics with this disease has been developed. Results and conclusion. Based on the study, risk groups for the development of HP-associated chronic gastroduodenitis were identified: asthenic girls over the age of 12, due to their tendency to more frequent development of the disease; girls and boys of the hypersthenic constitution type 4-17 years old, due to a more severe course of the disease and an insufficiently effective response to eradication antihelicobacter therapy. It is proposed to use symptomatic treatment (antispasmodics, antacids, prokinetics) as a starting therapy in children outside the risk group. In patients at risk, based on the results of an instrumental study, a decision is made on the appointment of a three-component or four-component eradication regimen.
DOI: 10.31146/1682-8658-ecg-245-1-33-40
Language: English
Field: Medicine
Open Access status: hybrid
OpenAlex ID: W7168519645
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Cites: 7
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Related to: 10