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Synthesis of 1,4-dihydropiridine Derivatives in Microwave Flow Reactor

Year: 2022

Type: conference-abstract

Abstract: 1,4-Dihydropyridine derivatives (e.g. Nimodipine, Nifedipine, Nitrendipine), which belong to the group of calcium channel blockers, serve as effective drugs in the treatment of cardiovascular diseases. According to the World Health Organization (WHO), this disease class ranks first in terms of the number of deaths worldwide. Considering the unfavorable statistics of mortality from cardiovascular diseases, which is about 17 million people per year, the development of unique, cost- effective methods of obtaining 1,4-dihydropyridine derivatives is an urgent task.

Source: Nazarbayev University Repository (Nazarbayev University)

Authors: Khrustaleva, Anastassiya, Khrustalev, Dmitriy, Yedrissov, Azamat, Mustafin, Marlen

Language: English

Topic: Microwave-Assisted Synthesis and Applications

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7197954869

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