Phenolic Compounds and Antioxidant and Cytotoxical Activities of Chaptalia Nutans (l.) Polack (asteraceae)
Year: 2026
Type: article
Abstract: Chaptalia nutans known as "arnica-do-campo", has broad popular use and its antibacterial, anti-inflammatory and colinergic activities are already proven.The crude extract, prepared through 70% hydroalcoholic maceration and fractions of leaves had been used to evaluate the citotoxicity, the antioxidant activity and the content of polyphenol of this plant.The ethyl acetate fraction presented the biggest polyphenol content (37.50 %) and also the highest antioxidant activity, with values next to the standard (ascorbic acid).The butanol fraction presented moderately toxic (CL 50 = 88.60 µg/ml), whereas the rude extract and the ethyl acetate and chloroform fractions had revealed little toxicity.
Authors: Pâmela Pozzer, Camila Ziliotto Zanotto, Stefane Ribeiro de Menezes, Gilberto Dolejal Zanetti, Elaine dos Anjos da Cruz da Rocha, Maria Fernanda Larcher de Almeida, Adriana Oliveira Gomes, Rita Cristina Azevedo Martins, Cherrine Kelce Pires, Edison Luis Santana Carvalho, Melânia Palermo Manfron
Language: English
Subfield: Plant Science
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W7201836729