Biomedical PCL Janus patch with mushroom-structured wet adhesive and PEG-coated anti-adhesive surface
Year: 2026
Type: article
Abstract: Simultaneously achieving tissue adhesion and anti-adhesion remains a fundamental challenge for biomedical patch development. Here, we developed a PCL-based Janus patch that combines wet adhesion mediated by mushroom-shaped microstructures with an anti-adhesive surface formed by UV-crosslinked PEG. The mushroom-structured surface enhanced wet adhesion, whereas the PEG-coated surface reduced nonspecific fibroblast attachment, enabling spatially separated adhesive and anti-adhesive functions within a single PCL platform.
Source: RSC Advances
DOI: 10.1039/d6ra06730a
Institution: Chonnam National University
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $1,042
Funders: National Research Foundation, Ministry of Agriculture, Food and Rural Affairs, National Research Foundation of Korea, Ministry of Science and ICT, South Korea, Commercializations Promotion Agency for R and D Outcomes, Korea Institute of Planning and Evaluation for Technology in Food, Agriculture and Forestry
OpenAlex ID: W7202192804