IVIMFitSlicer: an open-source 3D Slicer extension for multi-model intravoxel incoherent motion (IVIM) diffusion-MRI analysis
Year: 2026
Type: software-paper
Abstract: Intravoxel incoherent motion (IVIM) modelling separates tissue diffusion from microcapillary perfusion in diffusion-weighted MRI, but the estimated parameters depend strongly on the fitting model and algorithm, and most implementations are script-based and detached from interactive image-computing environments. We present IVIMFitSlicer, an open-source 3D Slicer extension that exposes six IVIM and diffusion models—mono-exponential, segmented and free bi-exponential, tri-exponential, and two Bayesian variants—within a single DICOM-aware workflow with automatic b-value extraction, region-of-interest and voxelwise parameter mapping, and interactive visualization. The extension recovers known parameters from a digital reference phantom under nine automated tests and is distributed through the official 3D Slicer Extension Manager under the MIT License.
Source: SoftwareX
Institution: Başkent University
Language: English
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $1,200
OpenAlex ID: W7202260437