Work

Transmission Dynamics of Antimicrobial Resistance in a Hospital Setting With External Importation

Year: 2026

Type: article

Abstract: We investigate the transmission dynamics of antimicrobial resistance in a hospital setting using a deterministic compartmental model with uncolonized and colonized patients and environmental bacterial load, incorporating external importation mediated by hospital visitors. The model is shown to be well-posed, and its equilibrium and stability are analyzed. The basic reproduction number is derived using the next-generation matrix method, and sensitivity analysis is performed. Numerical simulations are conducted to illustrate the analytical results. The findings show that external importation alters system behavior, eliminating classical threshold dynamics leading to persistent infection characterized by a unique positive equilibrium.

Source: Far East Journal of Mathematical Sciences (FJMS)

DOI: 10.17654/0972087126184

Authors: Johairiah M. Mangorangca, Harren J. Campos, Edward Aris D. Fajardo, Beverly B. Amparado, Fema M. Abamo

Institution: Mindanao State University

Language: English

Topic: Mathematical and Theoretical Epidemiology and Ecology Models

Subfield: Applied Mathematics

Field: Mathematics

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: Philippine Council for Health Research and Development, Science Education Institute, Department of Science and Technology, Republic of the Philippines