Psychological and cognitive support after cardiac arrest: a systematic review
Year: 2026
Type: review
Study design: Systematic Review
Abstract: Background: Adult survivors of cardiac arrest (CA) with favourable neurological recovery often experience persistent cognitive and psychological difficulties that impact quality of life and functional independence. However, post-discharge interventions remain heterogeneous, and evidence to support the prioritisation and implementation of specific cognitive and psychological interventions is limited. Objective: To systematically review the evidence on psychological and cognitive support interventions delivered after hospital discharge in adult CA survivors with good neurological recovery. Methods: A systematic review was conducted following PRISMA 2020 guidelines (PROSPERO CRD420251267160). Eligible studies included adults surviving CA with favourable neurological recovery who received structured post-discharge interventions. Outcomes were assessed across multiple domains, including: psychological well-being; cognitive performance; functional status and participation; health-related and global quality of life; and feasibility and implementation. Results: = 352 survivors) were included: two randomised controlled trials, two feasibility/pre-post studies, one single-case experimental design, and one process evaluation. Interventions varied in content and delivery (face-to-face, remote, home-based) and included nurse-led follow-up, psychotherapy, cognitive rehabilitation, and mindfulness-based strategies. Small improvements were observed in anxiety, depression, post-traumatic stress symptoms, and selected health-related quality-of-life domains, whereas cognitive, functional, and participation in daily and social activities showed limited or short-term gains in small uncontrolled studies. Interventions were feasible and well-tolerated. Conclusions: Post-discharge psychological and cognitive interventions are feasible and associated with modest improvements in psychological well-being and selected quality-of-life domains. Further rigorous research using standardised outcomes is needed.
Source: Resuscitation Plus
Institutions: Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda, Italian Resuscitation Council, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Provincia Autonoma di Trento, Agenzia Regionale Emergenza Urgenza, University of Milan, Azienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo, Agostino Gemelli University Polyclinic, Istituti di Ricovero e Cura a Carattere Scientifico, Ospedale Maggiore Carlo Alberto Pizzardi
Language: English
Subfield: Emergency Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,450
Funder: Italian Resuscitation Council
OpenAlex ID: W7203531980
