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Design and synthesis of the first PARP1 and PRMT5 dual inhibitors for the treatment of breast cancer

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Year: 2026
Type: article
Source: European Journal of Medicinal Chemistry
DOI: 10.1016/j.ejmech.2026.119231
Authors: Ying Xu, Qian Lei, Shuguang Yang, Yanxin Zhang, Xiangchao Luo, Xiaoping Song, Ningyu Wang, Qingchao Liu
Institutions: Northwest University, Sichuan University, West China Medical Center of Sichuan University, West China Hospital of Sichuan University, Southwest Jiaotong University
Language: English

Topic: PARP inhibition in cancer therapy
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: Natural Science Foundation of Shaanxi Province, Scientific Research Plan Projects of Shaanxi Education Department
Award: G6099340187
OpenAlex ID: W7203589370
FWCI:
Cites: 38
Cited by:
Related to: 10
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