ABO and Rh Blood Group Distribution in Blood Bank Populations: A Review with findings from the Mohali Region
Year: 2026
Type: peer-review
Abstract: This study provides a comprehensive review of the distribution, genetic basis, and clinical significance of ABO and Rh blood group systems, with particular emphasis on findings from the Mohali region of Punjab, India. The study uses data from a descriptive cross-sectional assessment of 500 individuals attending a blood bank in Mohali, where blood group O was the most prevalent (36%), followed by B (34%), A (22%), and AB (8%). Among Rh phenotypes, 92% of participants were Rh-positive and 8% were Rh-negative, with O-positive being the most common combined phenotype (33%) and AB-negative the least common (1%). The study further examines variations in ABO/Rh frequencies across Indian and global populations, explores the genetic mechanisms underlying these blood group systems, and discusses their importance in transfusion safety, blood-bank inventory management, pregnancy-related haemolytic disease, and disease-association research. The findings highlight considerable regional variation in blood group distribution and support the importance of population-specific data for effective blood-bank planning, donor recruitment, and transfusion services.
Institution: Guru Kashi University
Language: English
Topic: Blood groups and transfusion
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W7203589396