Year: 2024
Type: article
Study design: Observational Study
Abstract: Toxoplasmosis is a public health concern mostly among pregnant women in developping countries.The study aims to determine the seroprevalence of the infection on pregnant women, to identifywhether it is a recent or an old infection and to assess risk factors.A prospective and detailed survey was then conducted from July to October 2016 at the the integratedhealth centre of Mahabibo and the basic health centre of Tanambao Sotema in Mahajanga which is awest north city of Madagascar. The blood specimens were collected and then sent to the UniversityHospital Center Zafisaona Gabriel laboratory.In whole, 49 subjects were investigated with a mean age of 25 years old. The seroprevalence of the oldinfection (IgG+ and IgM-) was of 61% (n=30), non-immunized pregnant women (IgG- and IgM-)represented a rate of 39% (n=19). None of them was diagnosed with an acute infection (IgG+ andIgM+). No significant relation was associated between the infestation of Toxoplasma gondii andhousehold cats, neither with housekeeping occupation nor with education level, whether being awareor not of the infection (p>0.05).Toxoplasmosis is poorly known at Malagasy people. The seroprevalence in non-immunized pregnantwomen and those at risk is revealed to be high.
DOI: 10.71393/zk0s8g23
Authors: Rivo Rakotomalala, Francine Rakotonindrina, Mahefaniaina Jean Eustache Fanomezantsoa, Fanilo Rafilipojaona, Cathérine Razafindrakoto, Tahirimalala Rabenandrianina, Davidra Rajaonatahiana, Odilon Tiandaza, Norotiana Rabesandratana, Pierana Randaoharison, Rasoamialy Razanakolona, Olivat Rakoto Alson, Andry Rasamindrakotroka
Language: English
Subfield: Parasitology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W7203589778