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Pharmaceutical Formulation as a Dynamic System Linking Molecular Stability, Process History, Manufacturability, and In-Use Performance throughout the Product Lifecycle

Year: 2025

Type: article

Abstract: Pharmaceutical formulations are commonly described through composition, manufacturing specifications, critical quality attributes, and stability endpoints. Although these descriptions are necessary, they may inadequately represent products whose molecular organization, physical state, processability, release behavior, and in-use performance depend on the sequence of conditions experienced throughout the product lifecycle. This Original Dynamic-Systems Theory Article proposes that a pharmaceutica

Source: International Journal Of Pharmaceutical Research And Allied Sciences

DOI: 10.51847/lrzzlfshuw

Authors: Rafael Mendoza, Isabela Cruz, Carlos Lopez

Institutions: Universidad Nacional Autónoma de México, Tecnológico de Monterrey

Language: English

Topic: Drug Solubulity and Delivery Systems

Subfield: Pharmaceutical Science

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

Open Access status: hybrid

OpenAlex ID: W7203687005

FWCI:

Cites: 30

Cited by:

Related to: 10