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Cytotoxic immune activity reflects a coordinated immune microenvironment and is associated with response to total neoadjuvant therapy in rectal cancer

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Year: 2026
Type: article
Study design: Observational Study
Source: Journal of Gastroenterology
DOI: 10.1007/s00535-026-02502-5
Authors: Erina Haraguchi, Norio Tanaka, Kentaro Sato, Tatsuki Noguchi, Takashi Sakamoto, Shimpei Matsui, Toshiki Mukai, Tomohiro Yamaguchi, Eiji Shinozaki, Senzo Taguchi, Akiko Chino, Manabu Takamatsu, Ippei Fukada, Takayuki Ueno, Tetsuo Noda, Seiichi Mori, Takashi Akiyoshi
Institutions: Tohoku University, The Cancer Institute Hospital, Japanese Foundation For Cancer Research
Language: English

Topic: Colorectal Cancer Surgical Treatments
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: Japan Agency for Medical Research and Development, Japan Society for the Promotion of Science
Awards: TNT施行中の経時的scDNA解析による直腸がんクローン進化の解析と治療耐性機序の解明, 進行直腸がんに対するTNT後に臓器温存可能症例を正確に診断するシステムの構築, G7544233317, 直腸がんに対するTNT施行中の経時的scRNA解析による治療効果予測と耐性機序解明, G8756141430
OpenAlex ID: W7203702444
FWCI:
Cites: 35
Cited by:
Related to: 10
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