Wiki2Sirius
Year: 2026
Type: software
Abstract: Wiki2Sirius is a lightweight, zero-dependency web application that retrieves, live from Wikidata, the natural products reported for a given taxon, enriches them with chemical classification (NPClassifier) and XLogP / exact mass (PubChem), and exports the result as a SIRIUS custom structure database (TSV) or as an SDF file. No local database needs to be downloaded: every query (Wikidata SPARQL, taxon search, NPClassifier, PubChem) is performed live, at generation time, so results always reflect the current state of Wikidata. Main features Search a taxon by name or Wikidata QID SPARQL retrieval of compounds reported in the taxon and its sub-taxa, with bibliographic references Live chemical classification and XLogP annotation per compound Interactive results table (sorting, per-column filtering) Export as a self-contained HTML page, a SIRIUS custom structure database (.tsv), or a 2D-structure SDF file ImplementationWiki2Sirius is written in plain JavaScript for Node.js (≥18), with no external npm dependencies (only Node core modules and the native fetch). It ships with desktop launchers for macOS and Windows, and a standalone Windows build with Node.js embedded for users without a local Node.js installation. OriginThis project reimplements, in JavaScript, the approach of Adriano Rutz's R/Shiny tool wd-np-up-to-date, replacing its LOTUS bulk-download step with live Wikidata queries, and adding SIRIUS and SDF export formats. Source code : https://codeberg.org/simremy/Wiki2Sirius
Author: REMY, Simon
Institution: Université de Reims Champagne-Ardenne
Language: English
Subfield: Drug Discovery
Domain: Life Sciences
Open Access status: green
Funder: Agence Nationale de la Recherche
OpenAlex ID: W7203734664