Deep extubation versus no-touch awake extubation in adults undergoing elective laparotomy: A randomised controlled trial
Year: 2026
Type: article
Study designs: Randomized Controlled Trial, Clinical Trial
Abstract: Background and Aims: Tracheal extubation is a vulnerable phase of general anaesthesia. Smooth extubation strategies aim to reduce cough, bucking, and the sympathetic surge. This trial compared deep extubation with no-touch awake extubation in adults undergoing elective laparotomy. Methods: This prospective, randomised, partially outcome-assessor-blinded trial enroled American Society of Anesthesiologists (ASA) physical status I-II adults scheduled for elective laparotomy, allocated to deep extubation (Group D) or no-touch awake extubation (Group N). The primary outcome was cough (grade ≥1) within five minutes of extubation. Secondary outcomes were cough severity, airway adverse events, airway support, haemodynamics, and recovery characteristics. Results: = 0.028), greater need for airway support, and four re-intubations versus none. Recovery times were shorter in Group D. The heart rate and blood pressure were higher in Group N during early recovery. Conclusion: Deep extubation did not significantly reduce cough and was associated with more airway-related adverse events and airway support needs, including reintubation. Shorter recovery times and less moderate-to-severe cough in Group D did not reduce these risks. The findings do not support routine use of deep extubation and need confirmation in a larger, adequately powered trial.
Source: Indian Journal of Anaesthesia
Language: English
Subfield: Anesthesiology and Pain Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7203833459