Subthreshold micropulse laser treatment in patients with chronic central serous chorioretinopathy under prolonged stress
Year: 2026
Type: preprint
Study design: Clinical Trial
Abstract: Introduction This study purpose to evaluate the results of 577-nm subthreshold micropulse laser treatment in patients with chronic central serous chorioretinopathy under prolonged stress. Methods This study was a prospective, comparative, interventional, single-centre observation of 65 patients (65 eyes) with chronic central serous chorioretinopathy (CSC). All patients were divided into a civilian group (36 patients) and a military group (29 patients). All patients underwent subthreshold micropulse laser treatment (SMLT) using a laser with a wavelength of 577 nm. The main endpoint was best-corrected visual acuity (BCVA) at Months 12. Results Baseline mean BCVA in patients with chronic CSC was 0.66 (0.22). At Months 12, mean decimal BCVA statistically significantly increased to 0.74 (0.25) (p = 0.000). In military group, mean decimal BCVA increased statistically significantly from 0.65 (0.26) to 0.73 (0.25) (p = 0.01) at Month 12, and in civilian group – from 0.66 (0.18) to 0.77 (0.25) (p = 0.000). At the final visit, no significant difference was observed between mean decimal BCVA values in the two groups (p = 0.4). At Month 12, in overall cohort, complete resorption of subretinal fluid (SRF) was noted in 60% of cases (39 patients). In military group, complete resorption of SRF was observed in 52% of patients (15 patients) and in civilian group ‒ 67% (24 patients). No statistically significant difference between the groups in the frequency of complete resorption of SRF was found (p = 0.2). In overall cohort, mean of laser sessions of was 1.7 (0.7) during all observation period. In military group, mean number of SMLT sessions was 1.9 (0.9) and in the civilian group ‒ 1.4 (0.6). The difference between the groups in the number of laser sessions performed was statistically significant (p = 0.01). Conclusions SMLT is an effective and safe method for treating patients with chronic CSC under prolonged stress.
Source: Research Square
Language: English
Subfield: Ophthalmology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7203834073