Analytical Method Development and Validation for Simultaneous Estimation of Antidiabetic Drugs
Year: 2026
Type: article
Abstract: The present study describes the development and validation of a simple, rapid, precise, and stability-indicating UV method for the multicomponent analysis of Dapagliflozin Propanediol, Metformin Hydrochloride, and Teneligliptin Hydrobromide Hydrate in bulk materials and tablet dosage forms. Method validation was carried out in accordance with the International Council for Harmonisation (ICH) Q2(R1) guideline by evaluating specificity, linearity, accuracy, precision, repeatability, and assay. The validation results satisfied the recommended acceptance criteria, confirming the method's reliability and reproducibility. Owing to its simplicity, cost-effectiveness, and consistent performance, the proposed UV spectrophotometry method is well suited for routine quality control and assay of pharmaceutical formulations containing these three antidiabetic drugs.
Language: English
Subfield: Analytical Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: hybrid
OpenAlex ID: W7204056249