Clinical Outcomes of Pulsed Dye Laser in Port-wine Stains in Skin of Color: Experience from Nepal
Year: 2026
Type: article
Study design: Observational Study
Abstract: Pulsed dye laser (PDL) is the treatment of choice for port-wine stains (PWSs), but evidence from South Asian populations and darker skin types remains limited. To evaluate the clinical outcomes and safety of 595-nm PDL in patients with Fitzpatrick skin type IV treated for PWS at a tertiary dermatology center in Nepal. A retrospective case series of patients with PWS treated with 595-nm PDL between July 2022 and December 2024 was conducted. Treatment response was assessed using the Physician Global Assessment, and adverse effects were recorded. Twenty-five patients (mean age 26.1 ± 10.0 years) were included. All had Fitzpatrick skin type IV. After a mean of 5.5 treatment sessions, 20 (80%) achieved moderate to significant improvement, while near-complete clearance was seen in 2 (8%). Postinflammatory hyperpigmentation occurred in 3 (12%) and resolved with conservative management. No scarring or permanent pigmentary change was observed. PDL is a safe and effective treatment for PWS in Fitzpatrick skin type IV patients. This study adds important real-world evidence from Nepal and supports the use of PDL in skin of color when appropriate parameters are used.
Source: MEIDAM Association Journal
DOI: 10.4103/maj.maj_9_26
Institutions: Dhulikhel Hospital, Kathmandu University
Language: English
Subfield: Dermatology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W7204118930