Work

Minimal Residual Disease Assessment in Acute Lymphoblastic Leukemia: Methods for Detection and Quantification

Year: 2026

Type: review

Abstract: Recently, the identification of minimal residual disease (MRD), also known as measurable residual disease, has seen significant advances driven by the evolving technological landscape in this field. Initially based on raw morphology, the field has since evolved to incorporate karyotyping, cytogenetics, flow cytometry, and other sensitive methods. This updated review discusses key technical considerations for successful MRD detection. We explore the correlation between the results obtained by flow cytometry and molecular genetic techniques.

Source: Experimental Oncology

DOI: 10.15407/exp-oncology.2026.02.098

Authors: Sara Addakiri, Hanaa Bencharef, Asmaa Harrach, Samiha Jaddaoui, Khadija Ait-Ichou, Bouchra Oukkache

Institutions: University of Hassan II Casablanca, Centre Hospitalier Universitaire Ibn Rochd

Language: English

Topic: Acute Lymphoblastic Leukemia research

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W7204123568

FWCI:

Cites: 62

Cited by:

Related to: 10