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Congenital Hypertrophy of the Retinal Pigment Epithelium: Following the Bear Tracks

Year: 2026
Type: article
Abstract: Congenital hypertrophy of the retinal pigment epithelium (CHRPE) is a well-recognized benign ocular finding, characterized by flat, pigmented lesions. CHRPE lesions are typically unilateral and solitary but can also present as multiple or bilateral occurrences. They are relatively common, asymptomatic, and usually diagnosed incidentally during routine eye examinations. While generally benign, CHRPE or CHRPE-like lesions may warrant further evaluation to rule out systemic disorders such as familial adenomatous polyposis (FAP) or other differential diagnoses, especially in atypical or multiple lesions.
Authors: Freddy Lee, Amit Mishra
Language: English
Subfield: Ophthalmology
Field: Medicine
Open Access status: diamond
OpenAlex ID: W7204129673
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