Acute caffeine, endurance performance and metabolic responses: protocol for a systematic review and multilevel meta-analysis
Year: 2026
Type: preprint
Study design: Study Protocol
Abstract: Authors (in order): Chen Jiawei (Hunan Mechanical & Electrical Polytechnic; OSF profile display name: karl) and Gengli. Protocol version 0.1 (22 August 2026) for a systematic review and multilevel meta-analysis of acute caffeine, endurance performance, and exercise-related metabolic responses. Searches of PubMed, Embase, the Cochrane Library, Scopus, and Web of Science Core Collection were completed on 17 July 2026. Pilot screening, extraction, coding, or analytical outputs may have been generated during workflow development, but formal eligibility adjudication, the final analysis dataset, risk-of-bias judgements, and confirmatory analyses remain incomplete and subject to completion and verification. This is therefore an initial analysis plan rather than a strictly prospective preregistration. Amendments will be dated and explained. The review will include quantified administered-dose associations across caffeine administration routes; mg/kg refers to the amount administered or assigned, not absorbed or bioavailable dose.
Language: English
Topic: Coffee research and impacts
Subfield: Pharmacology (medical)
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7204192343