Replication Data for: Tissue corticosteroid rhythms are dysregulated mainly during sleep in primary aldosteronism
Year: 2025
Type: dataset
Abstract: This dataset contains hormone time series from a observational cohort study of patients with primary aldosteronism. Participants with unilateral primary aldosteronism [before and after adrenal surgery], bilateral primary aldosteronism, and indeterminate cause primary aldosteronism were sampled over 24-hours in ambulatory settings using a portable microdialysis sampling method. This generated, for each participant, a set of 72 samples of microdialysate, reflecting a 20-minute sampling resolution over 24-hours. Each sample was analysed using liquid chromatography-mass spectrometry in order to quantify corticosteroid hormones per time point. The primary outcome of the study was creation of 24-hour corticosteroid hormone profiles in ambulatory participants with primary aldosteronism.
Source: DataverseNO
DOI: 10.18710/iu4tlm
Authors: Grytaas, Marianne A., Upton, Thomas J., Marinelli, Isabella, Methlie, Paal, Øksnes, Marianne, Vassiliadi, Dimitra A., Bensing, Sophie, Russell, Georgina, Løvås, K, Margaritopoulos, D, Botusan, Ileana R., Simunkova, Katerina, Balomenaki, Maria, Berinder, Katarina, Lombard, Belinda, Sjøgren, Thea, Løvik, Ida, Oftedal, Bergithe E., Heie, Anette, Ueland, Grethe Å, Kämpe, Olle, Tsagarakis, Stylianos, Lightman, Stafford L., Zavala, E, Husebye, Eystein S.
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7204280115