A Comprehensive Approach to the Treatment of Elderly Patients With Acute Superficial Vein Thrombophlebitis
Year: 2026
Type: article
Study design: Clinical Trial
Abstract: Aim. To evaluate the efficacy and safety of a comprehensive treatment approach for high-risk superficial vein thrombophlebitis (SVT) in elderly and senile patients with contraindications to direct oral anticoagulants (DOACs). Material and methods. A prospective, open-label, bicenter study was conducted involving 65 patients aged over 60 years. All patients underwent crossectomy to prevent thrombus migration into the deep venous system. Patients were divided into two groups: Group 1 (n=30) received standard conservative therapy; Group 2 (n=35) received comprehensive treatment including phlebocementesis with thrombus evacuation, sclerotherapy using an original technique, and topical application of the multicomponent heparin-containing gel "Detragel". Efficacy was assessed by the dynamics of pain and edema (Visual Analogue Scale, VAS), hemostasis parameters, and quality of life (SF-36 questionnaire) at 12 months. Results. The application of the comprehensive protocol in Group 2 provided a significantly faster resolution of pain and edema. On postoperative day 7, pain severity was mild (2.3±0.3 points) versus moderate (4.1±0.6 points) in Group 1 (p<0.05). Edema was also less pronounced (1.9±0.6 points vs. 3.8±0.5; p<0.05). The study found no negative impact of sclerosing agents on the hemostasis system. In the long-term period, patients in Group 2 showed a statistically significant improvement in quality of life: vitality increased by 7.1 points (p=0.011), and the mental health component improved by 10.2 points (p=0.0012). Conclusion. The proposed comprehensive treatment method for acute thrombophlebitis, based on surgical evacuation of thrombotic masses, sclerotherapy, and topical therapy, is effective and safe. It accelerates the regression of clinical symptoms and provides a significant long-term improvement in patients' quality of life. Keywords: sclerosing agents, crossectomy, phlebocementesis, sclerotherapy,sodium heparin gel, Detragel, quality of life
Authors: B.S. Sukovatykh, A.V. Sereditsky, D.V. Sidorov
Language: English
Subfield: Internal Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W7204468566