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A Case of Kerion Celsi due to Trichophyton rubrum Successfully Treated with Fosravuconazole

Year: 2026

Type: article

Abstract: A male in his seventies presented with multiple erythematous follicular papules on the back, followed by lesions in the occipital region and posterior neck. Fungal examination revealed kerion celsi caused by Trichophyton rubrum. The patient was treated with fosravuconazole 100 mg/day for 8 weeks, and the brush method was negative 1 month later. The oral antifungal medicines approved for treatment of tinea capitis in Japan are limited to itraconazole and terbinafine hydrochloride. However, itraconazole has many contraindicated drugs, and antifungal resistance has recently become a major concern.As the challenge of drug-resistant fungi is expected to become more significant in the future, the clinical benefits of using fosravuconazole L-lysine ethanolate (F-RVCZ) for treating kerion celsi may increase. Our experience suggests that F-RVCZ could be a valuable therapeutic option.

Source: Medical Mycology Journal

DOI: 10.3314/mmj.26-00003

Authors: Chisato Une, Risa Ikutama, Rui Kano, Utako Kimura, Masataro Hiruma, Toshio Hasegawa

Institutions: Juntendo University Shizuoka Hospital, Teikyo University, Juntendo University, Ochanomizu Institute for Medical Mycology and Allergology

Language: English

Topic: Nail Diseases and Treatments

Subfield: Dermatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7204734738

FWCI:

Cites: 15

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Related to: 10